Diabetes en COVID-19: bewijs, huidige status en onbeantwoorde onderzoeksvragen.

Patiënten met diabetes die coronavirusziekte 2019 (COVID-19) krijgen, lopen een extreem ziekteverloop en sterfte. Verschillende elementen, met name de verminderde immuunrespons, verhoogde ontstekingsreactie en hypercoaguleerbare toestand, dragen bij tot de verhoogde ernst van de ziekte. Er zijn echter veel controversiële punten waarover het bewijs enigszins beperkt is.

Er zijn enkele theoretische overwegingen met betrekking tot de resultaten van verschillende anti-hyperglykemische medicatie. Evenzo, ongeacht de populariteit van angiotensine-veranderend enzym 2 (ACE2) omdat de receptor voor extreem acuut respiratoir syndroom coronavirus 2 (SARS CoV-2) en de functie van ACE2 bij longschade; er zijn tegenstrijdige resultaten bij het gebruik van angiotensine-veranderende enzym (ACE) -remmers en angiotensine-receptorblokkers (ARB) bij deze patiënten.

Het beheer van diabetespatiënten in geval van mobiliteitsbeperkingen stelt enkele uitdagingen en nieuwe benaderingen zoals telegeneeskunde kunnen nuttig zijn. Het zuivere beloop van COVID-19 bij diabetespatiënten moet verder worden onderzocht en de persoon moet worden begrepen, regionale en etnische verschillen in ziekteprevalentie en beloop.

Diabetes en COVID-19: bewijs, huidige status en onbeantwoorde onderzoeksvragen.

Patiënten met diabetes die coronavirusziekte 2019 (COVID-19) krijgen, lopen een extreem ziekteverloop en sterfte. Verschillende elementen, met name de verminderde immuunrespons, verhoogde ontstekingsreactie en hypercoaguleerbare toestand, dragen bij tot de verhoogde ernst van de ziekte.

Er zijn echter veel controversiële punten waarover het bewijs enigszins beperkt is. Er zijn enkele theoretische overwegingen met betrekking tot de resultaten van verschillende anti-hyperglykemische medicatie.

NP-40 Lysis Buffer 2X

22040064-3 500 mL
EUR 94.44

NP-40 Lysis Buffer 10%

22040073-1 100 mL
EUR 88.65

NP-40 Lysis Buffer 10%

22040073-2 500 mL
EUR 212.1

NP-40 Lysis Buffer 10%

22040073-3 1 L
EUR 339.83

NP-40 Lysis Buffer No Salt

22040046-1 250 mL
EUR 32.55

NP-40 Lysis Buffer No Salt

22040046-2 500 mL
EUR 63.5

NP-40 Lysis Buffer No Salt

22040046-3 1 L
EUR 96.98

NP-40 Lysis Buffer Low Salt

22040045-1 250 mL
EUR 38.72

NP-40 Lysis Buffer Low Salt

22040045-2 500 mL
EUR 63.5

NP-40 Lysis Buffer Low Salt

22040045-3 1 L
EUR 96.98

MES Lysis Buffer with NP-40

41320095-1 100 mL
EUR 33.33

MES Lysis Buffer with NP-40

41320095-2 250 mL
EUR 52.73

MES Lysis Buffer with NP-40

41320095-3 500 mL
EUR 85.01

MES Lysis Buffer with NP-40

41320095-4 1 L
EUR 106.79

NP-40 Lysis Buffer High Salt

22040044-1 250 mL
EUR 34.28

NP-40 Lysis Buffer High Salt

22040044-2 500 mL
EUR 53.25

NP-40 Lysis Buffer High Salt

22040044-3 1 L
EUR 98.27

HEPES Lysis Buffer with NP-40

40820045-1 100 mL
EUR 26.26

HEPES Lysis Buffer with NP-40

40820045-2 250 mL
EUR 51.85

HEPES Lysis Buffer with NP-40

40820045-3 500 mL
EUR 97.65

HEPES Lysis Buffer with NP-40

40820045-4 1 L
EUR 180.9

MES Lysis Buffer with NP-40 2X

41320096-1 125 mL
EUR 42.19

MES Lysis Buffer with NP-40 2X

41320096-2 250 mL
EUR 73.4

MES Lysis Buffer with NP-40 2X

41320096-3 500 mL
EUR 98.19

MES Lysis Buffer with NP-40 2X

41320096-4 1 L
EUR 145.03

HEPES Lysis Buffer with NP-40, 2X

40820046-1 125 mL
EUR 42.09

HEPES Lysis Buffer with NP-40, 2X

40820046-2 250 mL
EUR 59.03

HEPES Lysis Buffer with NP-40, 2X

40820046-3 500 mL
EUR 97.65

HEPES Lysis Buffer with NP-40, 2X

40820046-4 1 L
EUR 180.71

PIPES Lysis Buffer with NP-40 2X

41620175-1 125 mL
EUR 42.09

PIPES Lysis Buffer with NP-40 2X

41620175-2 250 mL
EUR 78.34

PIPES Lysis Buffer with NP-40 2X

41620175-3 500 mL
EUR 105.44

PIPES Lysis Buffer with NP-40 2X

41620175-4 1 L
EUR 202.68

HEPES Cell Lysis buffer with NP-40

H5100-100 100ml
EUR 141.6

NP-40 Lysis Buffer with Glycerol 2X

22040065-1 125 mL
EUR 35.43

NP-40 Lysis Buffer with Glycerol 2X

22040065-2 250 mL
EUR 58.64

NP-40 Lysis Buffer with Glycerol 2X

22040065-3 500 mL
EUR 94.44

PIPES Lysis Buffer with NP-40, pH 7.0

41620174-1 100 mL
EUR 26.07

PIPES Lysis Buffer with NP-40, pH 7.0

41620174-2 250 mL
EUR 53.29

PIPES Lysis Buffer with NP-40, pH 7.0

41620174-3 500 mL
EUR 78.22

PIPES Lysis Buffer with NP-40, pH 7.0

41620174-4 1 L
EUR 167.29

Lysis Buffer

abx098984-LysisBuffer120ml Lysis Buffer 1 (20 ml)
EUR 184.8

Lysis Buffer

abx098984-LysisBuffer3100ml Lysis Buffer 3 (100ml)
EUR 276

Lysis Buffer

abx098984-LysisBuffer420ml Lysis Buffer 4 (20 ml)
EUR 184.8

Lysis Buffer

abx098984-100l 100 µl
EUR 93.75

Lysis Buffer

abx098984-1ml 1 ml
EUR 93.75

Lysis Buffer

abx098984-200l 200 µl
EUR 93.75

Red Blood Cell Lysis Buffer,or ACK Lysis Buffer

ETF3702 120ml
EUR 24

IP Lysis Buffer

AR0107 100mL
EUR 121.2

WB Lysis Buffer

BMP2010-100mL 100 mL
EUR 59
Description: WB Lysis Buffer

WB Lysis Buffer

BMP2010-each each Ask for price

WB Lysis Buffer

BMP2010-Null Null Ask for price

RBC Lysis Buffer

18-448 125 mL/Unit
EUR 51.81
Description: Lysis of Red Blood Cells

RBC Lysis Buffer

18-449 250 mL/Unit
EUR 94.36
Description: Lysis of Red Blood Cells

RBC LYSIS BUFFER

IB47620 135ML
EUR 34.24

RBC LYSIS BUFFER

IB47621 200ML
EUR 50.69

RBC LYSIS BUFFER

IB47622 500ML
EUR 97.24

Tail Lysis Buffer

06169-95 500ML
EUR 61.6

Cell Lysis Buffer

1067-100 each
EUR 196.8

Cell Lysis Buffer

1067-400 each
EUR 352.8

Cell Lysis Buffer

AR0103 100mL (The kit contains sufficient lysis buffer for 200 cell pellet fractions containing 5x 106 cells each)
EUR 145.2

RIPA Lysis Buffer

AR0105 50 mL
EUR 90

Cell Lysis Buffer

GR103003 200 mL
EUR 54

Cell Lysis Buffer

TBS5001 40ml
EUR 55

Phage Lysis Buffer

30629559-1 100 mL
EUR 30.3

Phage Lysis Buffer

30629559-2 500 mL
EUR 41.52

Phage Lysis Buffer

30629559-3 1 L
EUR 55.68

Hypotonic Lysis Buffer

22050012-1 100 mL
EUR 46.28

Denaturing Lysis Buffer

22040027-1 250 mL
EUR 35.5

Denaturing Lysis Buffer

22040027-2 500 mL
EUR 56.21

Cell Lysis Buffer, 100ML

X050-100ML 100ML
EUR 70

WB (IP) Lysis Buffer

BMP2020-100mL 100 mL
EUR 59
Description: WB (IP) Lysis Buffer

WB (IP) Lysis Buffer

BMP2020-each each Ask for price

WB (IP) Lysis Buffer

BMP2020-Null Null Ask for price

10×ACK Lysis Buffer

E-CK-A105-100mL 100 mL
EUR 14

10×ACK Lysis Buffer

E-CK-A105-200mL 200 mL
EUR 20

10×ACK Lysis Buffer

E-CK-A105-500mL 500 mL
EUR 45

10×ACK Lysis Buffer

E-CK-A105-each each Ask for price

Tail Lysis Buffer 1

10450042-1 250 mL
EUR 44.22

Tail Lysis Buffer 1

10450042-2 500 mL
EUR 66.89

Tail Lysis Buffer 2

10450044-1 250 ml
EUR 33.33

Tail Lysis Buffer 2

10450044-2 500 ml
EUR 55.65

Tail Lysis Buffer 3

10450046-1 250 ml
EUR 33.33

Tail Lysis Buffer 3

10450046-2 500 ml
EUR 66.89

Tail Lysis Buffer 4

10450048-1 500 ml
EUR 55.77

ChIP Lysis Buffer III

10450058-1 100 mL
EUR 36.85

ChIP Lysis Buffer III

10450058-2 250 ml
EUR 54.54

ChIP SDS Lysis Buffer

22050031-1 10 mL Ask for price
Description: Chromatin Immunoprecipitation (ChIP) assays

ChIP SDS Lysis Buffer

22050031-2 25 mL Ask for price
Description: Chromatin Immunoprecipitation (ChIP) assays

CHAPS Lysis Buffer 1X

22050006-1 250 mL
EUR 51.7

CHAPS Lysis Buffer 1X

22050006-2 500 mL
EUR 82.5

CHAPS Lysis Buffer 2X

22050008-1 25 mL
EUR 46

CHAPS Lysis Buffer 2X

22050008-2 50 mL
EUR 75.74

CHAPS Lysis Buffer 2X

22050008-3 100 mL
EUR 109.98

RIPA Lysis Buffer (Weak)

abx090626-100ml 100 ml
EUR 260.4

RIPA Lysis Buffer (Weak)

abx090626-100l 100 µl
EUR 150

RIPA Lysis Buffer (Weak)

abx090626-1ml 1 ml Ask for price

RIPA Lysis Buffer (Weak)

abx090626-200l 200 µl Ask for price

Weak RIPA Lysis Buffer

EZPS05-1 100mL
EUR 13.8

CHAPS Cell Lysis Buffer

C2000-100 100ml
EUR 165.6

CHAPS Cell Lysis Buffer

C2000-500 500ml
EUR 400.8

5X Passive Lysis Buffer

99912 30ML
EUR 31
Description: N/A

5X Passive Lysis Buffer

99912-1 EA
EUR 31

1X Protein Lysis Buffer

G032 5.0 ml (5 x 1.0ml)
EUR 40

RIPA Lysis Buffer (Strong)

abx090624-100ml 100 ml
EUR 260.4

RIPA Lysis Buffer (Medium)

abx090625-100ml 100 ml
EUR 260.4

RIPA Lysis Buffer (Strong)

HY-K1001 100 mL
EUR 176.4

RIPA Lysis Buffer (Strong)

abx090624-100l 100 µl
EUR 150

RIPA Lysis Buffer (Strong)

abx090624-1ml 1 ml Ask for price

RIPA Lysis Buffer (Strong)

abx090624-200l 200 µl Ask for price

RIPA Lysis Buffer (Medium)

abx090625-100l 100 µl
EUR 150

RIPA Lysis Buffer (Medium)

abx090625-1ml 1 ml Ask for price

RIPA Lysis Buffer (Medium)

abx090625-200l 200 µl Ask for price

Formic Acid Lysis Buffer

22050063-1 250 mL
EUR 37.67

RIPA Lysis Buffer (Strong)

E-BC-R327-100mL 100mL
EUR 80

RIPA Lysis Buffer (Strong)

E-BC-R327-20mL 20mL
EUR 25

RIPA Lysis Buffer (Strong)

E-BC-R327-50mL 50mL
EUR 60

RIPA Lysis Buffer (Strong)

E-BC-R327-each each Ask for price

Strong RIPA Lysis Buffer

EZPS03-1 100mL
EUR 15

Medium RIPA Lysis Buffer

EZPS04-1 100mL
EUR 14.4

Lysis Buffer for Bacillus

22040042-1 100 mL
EUR 102.44

C to C Lysis Buffer

abx298007-5ml 5 ml
EUR 343.2

Exosomal Protein Lysis Buffer

P200P 2 ml
EUR 339

Exosomal Protein Lysis Buffer

P200P,-part-of-P200 - Ask for price

10 x Cell Lysis Buffer

GR103003x10 200 mL
EUR 118

Tail Lysis Buffer 1 2X

10450043-1 250 ml
EUR 66.89

Tail Lysis Buffer 1 2X

10450043-2 500 ml
EUR 109.54

Tail Lysis Buffer 2 2X

10450045-1 250 ml
EUR 33.33

Tail Lysis Buffer 2 2X

10450045-2 500 ml
EUR 100.34

Tail Lysis Buffer 3 2X

10450047-1 500 ml
EUR 109.54

Tail Lysis Buffer 4 2X

10450049-1 500 ml
EUR 100.34

1X Passive Lysis Buffer 2.0

99821 100ML
EUR 99.6
Description: Minimum order quantity: 1 unit of 100ML

1X Passive Lysis Buffer 2.0

99821-100ML 1ML
EUR 38
Description: BSA from bovine serum (cow; Bos taurus)

1X Passive Lysis Buffer 2.0

99821-100ML-1 EA
EUR 38

Red Blood Cell Lysis Buffer

abx090623-100ml 100 ml
EUR 226.8

Red Blood Cell Lysis Buffer

K1169-100 100ml
EUR 16
Description: The buffer is used for optimal lysis of erythrocytes in whole blood or tissues

Red Blood Cell Lysis Buffer

K1169-500 500ml
EUR 44
Description: The buffer is used for optimal lysis of erythrocytes in whole blood or tissues

Red Blood Cell Lysis Buffer

abx090623-100l 100 µl
EUR 125

Red Blood Cell Lysis Buffer

abx090623-1ml 1 ml Ask for price

Red Blood Cell Lysis Buffer

abx090623-200l 200 µl Ask for price

Triton X-114 Lysis Buffer

22050059-1 250 mL
EUR 41.96

Triton X-114 Lysis Buffer

22050059-2 500 mL
EUR 52.73

Immunoprecipitation IP Lysis Buffer

20831004-1 50 mL
EUR 37.06

Immunoprecipitation IP Lysis Buffer

20831004-2 100 mL
EUR 60.06

Immunoprecipitation IP Lysis Buffer

20831004-3 500 mL
EUR 90.69

10X RBC Lysis Buffer Solution

R075-100ML 1 unit
EUR 34.26
Description: 10X RBC Lysis Buffer Solution

10X RBC Lysis Buffer Solution

R075-500ML 1 unit
EUR 126.32
Description: 10X RBC Lysis Buffer Solution

White Blood Cell Lysis Buffer

40120343-1 250 ml
EUR 29.74

White Blood Cell Lysis Buffer

40120343-2 500 ml
EUR 47.35

MinuteTM RBC Lysis Buffer (250 ml)

WA-007 each
EUR 145

MagBead Viral RNA Lysis Buffer

BSV-COV each
EUR 583.2

MagBead Viral RNA Lysis Buffer

BSV-COV-B each
EUR 9676.8

Total Protein Cell Lysis Buffer

22050011-1 100 mL
EUR 103.49

ReadiUseâ„¢ Viral RNA Lysis Buffer

60015-50mL 50 mL
EUR 157
Description: Current demands for RT-PCR testing of SARS-CoV-2 have led to a worldwide shortage of RNA extraction kits.

ReadiUseâ„¢ Viral RNA Lysis Buffer

60016-500ML 500 ML
EUR 1019
Description: Current demands for RT-PCR testing of SARS-CoV-2 have led to a worldwide shortage of RNA extraction kits.

amfiSure Direct PCR Lysis Buffer

D0300-010 100ml
EUR 165.6

RIPA Lysis & Extraction Buffer

18-415 125 mL/Unit
EUR 91.18
Description: For lysis and protein solubili

RIPA Lysis & Extraction Buffer

18-416 250 mL/Unit
EUR 151.14
Description: For lysis and protein solubili

RIPA Lysis & Extraction Buffer

18-417 500 mL/Unit
EUR 308.82
Description: For lysis and protein solubili

5X Firefly Luciferase Lysis Buffer

99923 15ML
EUR 24
Description: N/A

5X Firefly Luciferase Lysis Buffer

99923-1 EA
EUR 24

OOTA00783-100ML - RBC Lysis Buffer

OOTA00783-100ML 100mL
EUR 59

T-Pro RIPA Lysis buffer (1X)

JT89-L001M 500ml/BT
EUR 60

T-Pro RIPA Lysis buffer (5X)

JT89-L005S 100ml/BT
EUR 60

Cell Lysis Buffer I for ChIP

10450053-1 100 ml
EUR 34.6

Cell Lysis Buffer I for ChIP

10450053-2 250 ml
EUR 54.54

Cell Lysis Buffer II for ChIP

10450054-1 100 ml
EUR 34.32

Cell Lysis Buffer II for ChIP

10450054-2 250 ml
EUR 54.54

Cell Lysis Buffer IV for ChIP

10450056-1 100 ml
EUR 34.32

Cell Lysis Buffer IV for ChIP

10450056-2 250 ml
EUR 54.54

1X Red Blood Cell Lysis Buffer

5830-100 each
EUR 105.6

Cell Lysis Buffer III for ChIP

10450055-1 100 ml
EUR 34.32

Evenzo, ongeacht de populariteit van angiotensine-veranderend enzym 2 (ACE2) omdat de receptor voor extreem acuut respiratoir syndroom coronavirus 2 (SARS CoV-2) en de functie van ACE2 bij longschade; er zijn tegenstrijdige resultaten bij het gebruik van angiotensine veranderende enzym (ACE) -remmers en angiotensine-receptorblokkers (ARB) bij deze patiënten.

Het beheer van diabetespatiënten in het geval van mobiliteitsbeperkingen vormt een aantal uitdagingen en nieuwe benaderingen zoals telegeneeskunde kunnen nuttig zijn. Er moet extra onderzoek worden gedaan naar het pure beloop van COVID-19 bij patiënten met diabetes en om de persoon, regionale en etnische verschillen in ziekteprevalentie en beloop te begrijpen.