Op bloed gebaseerde FTIR-ATR-spectroscopie in combinatie met extreme gradiëntversterking voor de diagnose van type 2-diabetes: een STARD-compatibel diagnoseonderzoek.

Tijdige analyse van diabetes type 2 en vroege interventie en therapie ervan zijn van vitaal belang voor het beheersen van metabole problemen, het vertragen en verminderen van problemen, het verminderen van sterfte en het verbeteren van een hoge kwaliteit van leven. Type 2 diabetes werd herkend door Fourier rework mid-infrarood (FTIR) verzwakte volledige reflectie (ATR) spectroscopie samen met overmatige gradiëntversterking (XGBoost).

Volbloed FTIR-ATR-spectra van 51 klinisch erkende diabetes type 2 en 55 gezonde vrijwilligers waren verzameld. Voor de gecompliceerde samenstelling van volledig bloed en verre spectrale ruis werd Savitzky-Golay-afvlakking voor het eerst toegepast op het FTIR-ATR-spectrum.

Vervolgens werd PCA gebruikt om overbodige kennis uit te roeien en verwierf het een van de beste variëteit aan receptonderdelen. Ten slotte werd het XGBoost-algoritme gebruikt om de soort 2-diabetes te onderscheiden van gezonde vrijwilligers en het grid-zoekalgoritme werd gebruikt om de gerelateerde parameters van de XGBoost-mannequin te optimaliseren om de robuustheid en generalisatiemiddelen van de mannequin te verbeteren.

De gevoeligheid van de optimale XGBoost-paspop was 95,23% (20/21), de specificiteit was 96,00% (24/25) en de nauwkeurigheid was 95,65% (44/46). De experimentele resultaten tonen aan dat FTIR-ATR-spectroscopie vermengd met XGBoost-algoritme diabetes type 2 snel en nauwkeurig kan diagnosticeren zonder reagentia.

Vermindering van de sterftekosten bij ouderen met diabetes: een overzicht van huidig ​​onderzoek.

Bij deze beoordeling wordt gekeken naar de mortaliteitslast die wordt opgemerkt bij de oudere inwoners van mensen met diabetes en worden de kanscomponenten geïdentificeerd die verband houden met het sterfterisico bij deze inwoners.

Het sterfte-gat tussen oudere mensen met en zonder diabetes blijft bestaan, waarbij de extra sterfte 10% hoger is dan binnen de normale bewoners. Hoewel de vroege sterfte bij mannen met diabetes aanzienlijk hoger is dan bij vrouwen met diabetes, is het relatieve sterfterisico bij vrouwen veel groter in vergelijking met meisjes zonder diabetes.

Oudere personen die diabetes hebben ontwikkeld op middelbare leeftijd hebben een aanzienlijk groter risico op sterfte in vergelijking met degenen die het ontwikkelen op verouderde leeftijd, wat de blijvende betekenis benadrukt van het optimaliseren van diabeteszorg op alle leeftijden.

Novobiocin sodium

N014-1G 1 g
EUR 78

Novobiocin sodium

N014-5G 5 g
EUR 188.4

Novobiocin (Sodium)

HY-B0425A 10mM/1mL
EUR 223.2

Novobiocin Supplement

MED1556 PK10
EUR 57.12

Novobiocin Sodium Salt

B1526-1G each
EUR 130.8

Novobiocin Sodium Salt

B1526-5G each
EUR 288

Novobiocin sodium salt

GA5711-1G 1 g
EUR 84

Novobiocin sodium salt

GA5711-5G 5 g
EUR 199.2

TSB w Novobiocin-20mg/L

MED1130 PK50
EUR 54

Novo-TRX

27500 20 µl
EUR 335
Description: Novobiocin is an aminocoumarin antibiotic that is produced by Streptomyces niveus. Along with other aminocoumarin antibiotics, novobiocin is a very potent inhibitor of bacterial DNA gyrase. It works by targeting the GyrB subunit of the enzyme involved in energy transduction. Novo-TRX is Texas Red-labeled novobiocin, which can be used as a fluorescence probe in assays for screening DNA gyrase inhibitors.

Novo? cDNA Kit

M1165-100 each
EUR 424.8

Novo? cDNA Kit

M1165-25 each
EUR 320.4

Novo? Two Step RT Kit

M1161-100 each
EUR 457.2

Novo? Two Step RT Kit

M1161-25 each
EUR 320.4

Novokinin

B5461-1 1 mg
EUR 350.4

Novo? cDNA Supermix

M1169-100 each
EUR 529.2

Novo? cDNA Supermix

M1169-25 each
EUR 346.8

Novo? Transcriptome cDNA Kit

M1167-100 each
EUR 1142.4

Novo? Transcriptome cDNA Kit

M1167-25 each
EUR 529.2

Novo? Reverse Transcriptase

M1174-100 each
EUR 457.2

Novo? Reverse Transcriptase

M1174-25 each
EUR 385.2

MK TETRATHIONATE NOVO COMPLETE

MED1114 PK50
EUR 58.8

Recombinant Human Fibronectin Fragment/RetroNectin/NovoNectin

CH38-10ug 10ug
EUR 96
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Fibronectin Fragment/RetroNectin/NovoNectin

CH38-1mg 1mg
EUR 522
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Fibronectin Fragment/RetroNectin/NovoNectin

CH38-500ug 500ug
EUR 375.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Fibronectin Fragment/RetroNectin/NovoNectin

CH38-50ug 50ug
EUR 157.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Nov/ Rat Nov ELISA Kit

ELI-35315r 96 Tests
EUR 1063.2

Nova1/ Rat Nova1 ELISA Kit

ELI-44616r 96 Tests
EUR 1063.2

LKB Pharmacia Ultrospec 2000 3000 Novaspec ii Tungsten Lamp

LT-LKB-100 EACH
EUR 49.2

Chicken Protein NOV, NOV ELISA KIT

ELI-38132c 96 Tests
EUR 1113.6

Rat Protein NOV homolog(NOV) ELISA kit

CSB-EL015956RA-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat Protein NOV homolog (NOV) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Protein NOV homolog(NOV) ELISA kit

1-CSB-EL015956RA
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Protein NOV homolog(NOV) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Protein NOV Homolog (NOV) Antibody

20-abx214413
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Protein NOV Homolog (NOV) Antibody

20-abx325508
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Protein NOV Homolog (NOV) Antibody

20-abx320575
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Protein NOV Homolog (NOV) Antibody

20-abx006766
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Human Protein NOV homolog(NOV) ELISA kit

CSB-EL015956HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Human Protein NOV homolog (NOV) in samples from serum, plasma, tissue homogenates . A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Protein NOV homolog(NOV) ELISA kit

1-CSB-EL015956HU
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human Protein NOV homolog(NOV) in samples from serum, plasma, tissue homogenates . Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Protein NOV homolog(NOV) ELISA kit

CSB-EL015956MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Protein NOV homolog (NOV) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Protein NOV homolog(NOV) ELISA kit

1-CSB-EL015956MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Protein NOV homolog(NOV) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Protein NOV homolog, NOV ELISA KIT

ELI-35314h 96 Tests
EUR 988.8

Mouse Protein NOV homolog, Nov ELISA KIT

ELI-14991m 96 Tests
EUR 1038

NOVATest Antigen Rapid Kit (NOVA Test)

nCov-500 20 Tests
EUR 162

Mouse Protein NOV Homolog (NOV) Protein

20-abx261807
  • EUR 5238.00
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Human Protein NOV Homolog (NOV) Protein

20-abx261834
  • EUR 5254.80
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Human RNA- binding protein Nova- 2, NOVA2 ELISA KIT

ELI-36919h 96 Tests
EUR 988.8

Human RNA- binding protein Nova- 1, NOVA1 ELISA KIT

ELI-21240h 96 Tests
EUR 988.8

Mouse RNA- binding protein Nova- 1, Nova1 ELISA KIT

ELI-22111m 96 Tests
EUR 1038

NOVATest IgG/IgM Antibody Rapid Test Kit (NOVA Test)

UNCOV-40 40 Tests
EUR 115

ELISA kit for Human RNA-binding protein Nova-2 (NOVA2)

KTE62364-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human RNA-binding protein Nova-2 (NOVA2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human RNA-binding protein Nova-2 (NOVA2)

KTE62364-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human RNA-binding protein Nova-2 (NOVA2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human RNA-binding protein Nova-2 (NOVA2)

KTE62364-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human RNA-binding protein Nova-2 (NOVA2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

NOVATest Antigen Rapid Test Kit (For Single Use) (NOVA Test)

nCov-500-01 1T
EUR 162

NOV siRNA

20-abx926185
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

NOV siRNA

20-abx926186
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

NOV siRNA

20-abx903608
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

NOVA Alternative Splicing Regulator 2 (NOVA2) Antibody

abx235802-100ug 100 ug
EUR 610.8

NOVA Alternative Splicing Regulator 2 (NOVA2) Antibody

abx029973-400ul 400 ul
EUR 627.6

NOVA Alternative Splicing Regulator 2 (NOVA2) Antibody

abx029973-80l 80 µl
EUR 343.2

Human NOVA Alternative Splicing Regulator 2 (NOVA2) ELISA Kit

abx381853-96tests 96 tests
EUR 1093.2

NOV Rabbit pAb

A5320-100ul 100 ul
EUR 369.6

NOV Rabbit pAb

A5320-200ul 200 ul
EUR 550.8

NOV Rabbit pAb

A5320-20ul 20 ul
EUR 219.6

NOV Rabbit pAb

A5320-50ul 50 ul
EUR 267.6

NOV Rabbit pAb

A14488-100ul 100 ul
EUR 369.6

NOV Rabbit pAb

A14488-200ul 200 ul
EUR 550.8

NOV Rabbit pAb

A14488-20ul 20 ul
EUR 219.6

NOV Rabbit pAb

A14488-50ul 50 ul
EUR 267.6

NOV protein

30R-AN038 20 ug
EUR 327.6
Description: Purified recombinant Human NOV protein

NOVA1 siRNA

20-abx926182
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

NOVA1 siRNA

20-abx926183
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

NOVA2 siRNA

20-abx926184
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

NOV antibody

70R-1714 100 ug
EUR 452.4
Description: Rabbit polyclonal NOV antibody raised against the middle region of NOV

NOV antibody

70R-1715 100 ug
EUR 452.4
Description: Rabbit polyclonal NOV antibody raised against the C terminal of NOV

NOV antibody

70R-NR012 50 ug
EUR 327.6
Description: Affinity purified Rabbit polyclonal NOV antibody

NOV Antibody

36547-100ul 100ul
EUR 302.4

NOV Antibody

1-CSB-PA005674
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NOV. Recognizes NOV from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

NOV Antibody

1-CSB-PA015956ESR2HU
  • EUR 266.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against NOV. Recognizes NOV from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

NOV Antibody

1-CSB-PA987170
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against NOV. Recognizes NOV from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:500-1:2000, IHC:1:25-1:100

Novaluron

HY-17519 100mg
EUR 325.2

NOVA1 Peptide

46-694P 0.1 mg
EUR 405.6
Description: NOVA1 Peptide

NOVA1 Rabbit pAb

A12030-100ul 100 ul
EUR 369.6

NOVA1 Rabbit pAb

A12030-200ul 200 ul
EUR 550.8

NOVA1 Rabbit pAb

A12030-20ul 20 ul
EUR 219.6

NOVA1 Rabbit pAb

A12030-50ul 50 ul
EUR 267.6

NOV ELISA KIT|Human

EF001289 96 Tests
EUR 826.8

Gloria Nova HS PCR Kit

RK20714 20 RXNS Ask for price

NOVA2 antibody

70R-1370 100 ug
EUR 452.4
Description: Rabbit polyclonal NOVA2 antibody raised against the middle region of NOVA2

NOVA1 antibody

70R-12687 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal NOVA1 antibody

NOVA2 antibody

70R-18929 50 ul
EUR 522
Description: Rabbit polyclonal NOVA2 antibody

NOVA2 antibody

70R-1469 100 ug
EUR 452.4
Description: Rabbit polyclonal NOVA2 antibody raised against the N terminal of NOVA2

NOVA1 antibody

22767-100ul 100ul
EUR 468

NOVA1 antibody

70R-4832 50 ug
EUR 560.4
Description: Rabbit polyclonal NOVA1 antibody raised against the C terminal of NOVA1

NOVA1 antibody

70R-5002 50 ug
EUR 560.4
Description: Rabbit polyclonal NOVA1 antibody raised against the middle region of NOVA1

NOVA1 Antibody

1-CSB-PA015957LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NOVA1. Recognizes NOVA1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

NOVA2 Antibody

1-CSB-PA015958GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against NOVA2. Recognizes NOVA2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

Nova1 Antibody

DF14153 100ul
EUR 420

NOVA2 Antibody

DF15644 100ul
EUR 420

Novel Green PLUS (20000X)

LD003-0500 500 µl
EUR 206.4

Novel Green PLUS (20000X)

LD003-0500L 5x500 µl
EUR 877.2

anti- NOV antibody

FNab05801 100µg
EUR 606.3
Description: Antibody raised against NOV

Nov ORF Vector (Rat) (pORF)

ORF071423 1.0 ug DNA
EUR 607.2

NOVA1 Antibody

RQ4592 100ug
EUR 356.15
Description: RNA-binding protein Nova-1 is a protein that in humans is encoded by the NOVA1 gene. It is mapped to 14q12. This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.

NOVA2 Antibody

RQ5998 100 ug
EUR 356.15
Description: NOVA alternative splicing regulator 2 is a protein that in humans is encoded by the NOVA2 gene. It is mapped to 19q13.32. NOVA2 may regulate RNA splicing or metabolism in a specific subset of developing neurons. It binds single strand RNA.

NOVA1 Antibody

R35595-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Neuro-oncological ventral antigen 1

NOVATest VAPERON Neutralizing Antibody Rapid Detection Kit (NOVA Test)

COVNA-503 20 Tests Ask for price

Rat NOV shRNA Plasmid

20-abx986601
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human NOV/CCN3 ELISA Kit

LF-EK50926 1×96T
EUR 777.6

NOVA2 ELISA KIT|Human

EF001290 96 Tests
EUR 826.8

NOV cloning plasmid

CSB-CL015956HU-10ug 10ug
EUR 493.2
Description: A cloning plasmid for the NOV gene.

NOV ORF Vector (Human) (pORF)

ORF007166 1.0 ug DNA
EUR 114

ELISA kit for Human NOV/CCN3

EK5373 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human NOV/CCN3 in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Mouse NOV/CCN3

EK5374 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse NOV/CCN3 in samples from serum, plasma, tissue homogenates and other biological fluids.

anti- NOVA2 antibody

FNab05802 100µg
EUR 658.5
Description: Antibody raised against NOVA2

Nov ORF Vector (Mouse) (pORF)

ORF051542 1.0 ug DNA
EUR 607.2

Gloria Nova HS 2x Master Mix

RK20717 1mL Ask for price

NOV 3'UTR GFP Stable Cell Line

TU065842 1.0 ml
EUR 1672.8

Nov 3'UTR GFP Stable Cell Line

TU264097 1.0 ml Ask for price

Nov 3'UTR GFP Stable Cell Line

TU164225 1.0 ml Ask for price

Mouse NOV shRNA Plasmid

20-abx971787
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

NOV Blocking Peptide

33R-8084 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of NOV antibody, catalog no. 70R-1714

NOV Blocking Peptide

33R-4680 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of NOV antibody, catalog no. 70R-1715

Human NOV shRNA Plasmid

20-abx953228
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Nori® Human NOV/CCN3 ELISA Kit

GR106385 96-well
EUR 461

NOV ELISA Kit (Rat) (OKCA00996)

OKCA00996 96 Wells
EUR 999.6
Description: Description of target: Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival. Acts by binding to integrins or membrane receptors such as NOTCH1. Essential regulator of hematopoietic stem and progenitor cell function. Inhibits myogenic differentiation through the activation of Notch-signaling pathway. Inhibits vascular smooth muscle cells proliferation by increasing expression of cell-cycle regulators such as CDKN2B or CDKN1A independently of TGFB1 signaling. Ligand of integrins ITGAV:ITGB3 and ITGA5:ITGB1, acts directly upon endothelial cells to stimulate pro-angiogenic activities and induces angiogenesis. In endothelial cells, supports cell adhesion, induces directed cell migration (chemotaxis) and promotes cell survival. Plays also a role in cutaneous wound healing acting as integrin receptor ligand. Supports skin fibroblast adhesion through ITGA5:ITGB1 and ITGA6:ITGB1 and induces fibroblast chemotaxis through ITGAV:ITGB5. Seems to enhance bFGF-induced DNA synthesis in fibroblasts. Involved in bone regeneration as a negative regulator. Enhances the articular chondrocytic phenotype, whereas it repressed the one representing endochondral ossification . Impairs pancreatic beta-cell function, inhibits beta-cell proliferation and insulin secretion. Plays a role as negative regulator of endothelial pro-inflammatory activation reducing monocyte adhesion, its anti-inflammatory effects occur secondary to the inhibition of NF-kappaB signaling pathway. Contributes to the control and coordination of inflammatory processes in atherosclerosis. Attenuates inflammatory pain through regulation of IL1B- and TNF-induced MMP9, MMP2 and CCL2 expression. Inhibits MMP9 expression through ITGB1 engagement .;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 7.81 ng/mL

NOVA1 ORF Vector (Human) (pORF)

ORF026185 1.0 ug DNA
EUR 114

NOVA2 ORF Vector (Human) (pORF)

ORF026187 1.0 ug DNA Ask for price

Nova1 ORF Vector (Mouse) (pORF)

ORF051543 1.0 ug DNA
EUR 607.2

Nova2 ORF Vector (Mouse) (pORF)

ORF051544 1.0 ug DNA
EUR 607.2

NOVA1 3'UTR GFP Stable Cell Line

TU065843 1.0 ml
EUR 1825.2

NOVA2 3'UTR GFP Stable Cell Line

TU065844 1.0 ml
EUR 1672.8

Nova1 3'UTR GFP Stable Cell Line

TU264098 1.0 ml Ask for price

Nova2 3'UTR GFP Stable Cell Line

TU264099 1.0 ml Ask for price

Nova1 3'UTR GFP Stable Cell Line

TU164226 1.0 ml Ask for price

Nova2 3'UTR GFP Stable Cell Line

TU164227 1.0 ml Ask for price

Mouse NOVA1 shRNA Plasmid

20-abx984227
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Nova Microcinerator

ARG1776 EACH
EUR 306.66

NOVA1 Blocking Peptide

33R-9210 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of NOVA1 antibody, catalog no. 70R-5002

NOVA2 Blocking Peptide

33R-2631 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of NOVA2 antibody, catalog no. 70R-1370

NOVA2 Blocking Peptide

33R-5942 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of NOVA2 antibody, catalog no. 70R-1469

NOVA1 Blocking Peptide

33R-8555 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of NOVA1 antibody, catalog no. 70R-4832

Norovirus (NOV) Antibody

abx023841-1mg 1 mg
EUR 1011.6

Norovirus (NOV) Antibody

abx023842-1mg 1 mg
EUR 1011.6

Norovirus (NOV) Antibody

abx023843-1mg 1 mg
EUR 1011.6

Norovirus (NOV) Antibody

abx023844-1mg 1 mg
EUR 1011.6

Norovirus (NOV) Antibody

abx023845-1mg 1 mg
EUR 1011.6

Norovirus (NOV) Antibody

abx023846-1mg 1 mg
EUR 1011.6

Norovirus (NOV) Antibody

abx023847-1mg 1 mg
EUR 1011.6

Norovirus (NOV) Antibody

abx022119-1mg 1 mg
EUR 1128

Norovirus (NOV) Antibody

abx022120-1mg 1 mg
EUR 1128

Human NOVA1 shRNA Plasmid

20-abx953229
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human NOVA2 shRNA Plasmid

20-abx953230
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

NOV Recombinant Protein

92-639 0.05 mg
EUR 481.2
Description: NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor-binding protein (IGFBP) domain, von Willebrand type C (VWC) domain, thrombospondin-1 (TSP-1) domain, and C-terminal (CT) domain (absent in CCN5). By specific interactions with these domains, CCN proteins modulate multiple signalling pathways including BMPs, Wnt, TGFs, Notch and integrins to regulate cell proliferation, differentiation, adhesion, migration, angiogenesis, and survival. CCN3 is firstly characterized as a promoter of progenitor activity of human hematopoietic stem cells, as knockdown of CCN3 can abrogate the function of primitive progenitors. Recent studies showed that CCN3 is also actively involved in the process of wound healing. CCN3 is highly expressed in granulation tissues of cutaneous wounds and capable of inducing synthetic responses of fibroblasts.

El Paper Novablot 200x250Mm P 500

80110619 EACH
EUR 488.4

Nov Polyclonal Antibody

ABP53143-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Nov from Human, Mouse. This Nov antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Nov

Nov Polyclonal Antibody

ABP53143-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Nov from Human, Mouse. This Nov antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Nov

Nov Polyclonal Antibody

ABP53143-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Nov from Human, Mouse. This Nov antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Nov

BRAND(TM) DESSICATOR NOVUS LID W

BR65738-1EA EACH
EUR 153.6

NOV Recombinant Protein

40-222-0005mg 0.005 mg
EUR 311.1
Description: NOV is a member of the CCN family of secreted cysteine rich regulatory proteins. The full length NOV protein contains four structural domains that confer distinct, and sometimes opposing, biological activities. Elevated expression of NOV is associated with certain tumors, including Wilm’s tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorgenicity and proliferation is correlated with decreased NOV expression. Additionally, NOV induces cell adhesion and cell migration by signaling through specific cell surface integrins and by binding to heparin sulfate proteoglycans and to fibulin 1C. NOV has also been reported to exert proangiogenic activities. Recombinant human NOV is a 36.2 kDa protein containing 331 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the Thrombospondin type-I (TSP type-1) domain, and a C-terminal cysteine knot-like domain (CTCK).

NOV Recombinant Protein

40-222-002mg 0.02 mg
EUR 437.1
Description: NOV is a member of the CCN family of secreted cysteine rich regulatory proteins. The full length NOV protein contains four structural domains that confer distinct, and sometimes opposing, biological activities. Elevated expression of NOV is associated with certain tumors, including Wilm’s tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorgenicity and proliferation is correlated with decreased NOV expression. Additionally, NOV induces cell adhesion and cell migration by signaling through specific cell surface integrins and by binding to heparin sulfate proteoglycans and to fibulin 1C. NOV has also been reported to exert proangiogenic activities. Recombinant human NOV is a 36.2 kDa protein containing 331 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the Thrombospondin type-I (TSP type-1) domain, and a C-terminal cysteine knot-like domain (CTCK).

Nov Polyclonal Antibody

41797-100ul 100ul
EUR 302.4

Nov Polyclonal Antibody

41797-50ul 50ul
EUR 224.4

Mouse Norovirus (NoV) ELISA Kit

abx055035-96tests 96 tests
EUR 801.6

Human Norovirus (NoV) ELISA Kit

abx055762-96tests 96 tests
EUR 801.6

NOV Conjugated Antibody

C36547 100ul
EUR 476.4

NOV ELISA Kit (Mouse) (OKCA01755)

OKCA01755 96 Wells
EUR 1015.2
Description: Description of target: Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival. Acts by binding to integrins or membrane receptors such as NOTCH1. Essential regulator of hematopoietic stem and progenitor cell function. Inhibits myogenic differentiation through the activation of Notch-signaling pathway. Inhibits vascular smooth muscle cells proliferation by increasing expression of cell-cycle regulators such as CDKN2B or CDKN1A independently of TGFB1 signaling. Ligand of integrins ITGAV:ITGB3 and ITGA5:ITGB1, acts directly upon endothelial cells to stimulate pro-angiogenic activities and induces angiogenesis. In endothelial cells, supports cell adhesion, induces directed cell migration (chemotaxis) and promotes cell survival. Plays also a role in cutaneous wound healing acting as integrin receptor ligand. Supports skin fibroblast adhesion through ITGA5:ITGB1 and ITGA6:ITGB1 and induces fibroblast chemotaxis through ITGAV:ITGB5. Seems to enhance bFGF-induced DNA synthesis in fibroblasts. Involved in bone regeneration as a negative regulator (PubMed:23653360). Enhances the articular chondrocytic phenotype, whereas it repressed the one representing endochondral ossification. Impairs pancreatic beta-cell function, inhibits beta-cell proliferation and insulin secretion (PubMed:23705021). Plays a role as negative regulator of endothelial pro-inflammatory activation reducing monocyte adhesion, its anti-inflammatory effects occur secondary to the inhibition of NF-kappaB signaling pathway. Contributes to the control and coordination of inflammatory processes in atherosclerosis (PubMed:24722330). Attenuates inflammatory pain through regulation of IL1B- and TNF-induced MMP9, MMP2 and CCL2 expression. Inhibits MMP9 expression through ITGB1 engagement.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sanadwich ELISA;Sensitivity: 5.85 pg/mL

Nov Polyclonal Antibody

ES4142-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Nov from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Nov Polyclonal Antibody

ES4142-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Nov from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

NOV ELISA Kit (Human) (OKBB00827)

OKBB00827 96 Wells
EUR 606
Description: Description of target: NOV(nephroblastoma overexpressed), also known as CCN3, is a matricellular protein that in humans is encoded by the NOV gene. The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. This gene is mapped to 8q24.12. NOV is a potentially useful marker for the diagnosis of adrenal gland diseases, malignant adrenocortical tumors, multiple sclerosis and so on. Moreover, reduced expression of NOV in ACTs may play an important role in the process of childhood ACT tumorigenesis. Though studying, it identified Nov as a regulator of human hematopoietic stem or progenitor cells.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <2pg/ml

NOV ELISA Kit (Mouse) (OKBB00828)

OKBB00828 96 Wells
EUR 606
Description: Description of target: NOV (nephroblastoma overexpressed), also known as CCN3, is a matricellular protein that in humans is encoded by the NOV gene. The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. This gene is mapped to 8q24.12. NOV is a potentially useful marker for the diagnosis of adrenal gland diseases, malignant adrenocortical tumors, multiple sclerosis and so on. Moreover, reduced expression of NOV in ACTs may play an important role in the process of childhood ACT tumorigenesis. Though studying, it identified Nov as a regulator of human hematopoietic stem or progenitor cells.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

Nov Protein Vector (Rat) (pPM-C-HA)

PV285692 500 ng
EUR 723.6

Nori® Human NOV/CCN3 ELISA Kit (2 plates)

GR106385-2 2 x 96-well
EUR 832

Human NOV/CCN3 PicoKine ELISA Kit

EK0833 96 wells
EUR 510
Description: For quantitative detection of human NOV in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Mouse NOV/CCN3 PicoKine ELISA Kit

EK0834 96 wells
EUR 510
Description: For quantitative detection of mouse NOV in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

NOVA1-AS1 ORF Vector (Human) (pORF)

ORF026186 1.0 ug DNA Ask for price

Nov Protein Vector (Rat) (pPB-C-His)

PV285690 500 ng
EUR 723.6

Nov Protein Vector (Rat) (pPB-N-His)

PV285691 500 ng
EUR 723.6

Nov Protein Vector (Rat) (pPM-C-His)

PV285693 500 ng
EUR 723.6

Recombinant NoV VP1 Protein

VAng-Wyb3670-50g 50 µg
EUR 1693.2
Description: Norovirus VP1, recombinant protein.

NOVA1 Polyclonal Antibody

27594-100ul 100ul
EUR 302.4

NOVA1 Polyclonal Antibody

27594-50ul 50ul
EUR 224.4

Nov Protein Vector (Human) (pPM-C-HA)

PV028663 500 ng
EUR 394.8

Nov Protein Vector (Mouse) (pPM-C-HA)

PV206168 500 ng
EUR 723.6

Recombinant NoV VP2 Protein (aa 21-275) [His]

VAng-Wyb3653-100g 100 µg
EUR 4002
Description: Norovirus (strain swine/GII/OH-QW125/03/US) VP2 protein, recombinant protein.

Recombinant NoV VP2 Protein (aa 21-275) [His]

VAng-Wyb3653-500g 500 µg
EUR 9794.4
Description: Norovirus (strain swine/GII/OH-QW125/03/US) VP2 protein, recombinant protein.

Nova Microcinerator Loop Rest

ARG1774 EACH
EUR 39.82

NOVA1 Antibody, HRP conjugated

1-CSB-PA015957LB01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NOVA1. Recognizes NOVA1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

NOV ELISA Kit (Human) : 96 Wells (OKAG00054)

OKAG00054 96 Wells
EUR 715.2
Description: Description of target: The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 63 pg/mL

Recombinant Human NOV Protein

PROTP48745-2 20ug
EUR 380.4
Description: NOV is a member of the CCN family of secreted cysteine rich regulatory proteins. The full length NOV protein contains four structural domains that confer distinct, and sometimes opposing, biological activities. Elevated expression of NOV is associated with certain tumors, including Wilm’s tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorgenicity and proliferation is correlated with decreased NOV expression. Additionally, NOV induces cell adhesion and cell migration by signaling through specific cell surface integrins and by binding to heparin sulfate proteoglycans and to fibulin 1C. NOV has also been reported to exert proangiogenic activities. Recombinant human NOV is a 36.2 kDa protein containing 331 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the Thrombospondin type-I (TSP type-1) domain, and a C-terminal cysteine knot-like domain (CTCK).

Om het sterfterisico op oudere leeftijd te verminderen, is het een zeer belangrijke aanpak van de componenten die gevaar opleveren, namelijk: comorbiditeit; polyfarmacie; lichamelijke en psychologische kwetsbaarheid; beschermde glycemische doelen voor oudere mensen ; hypoglykemie; glycemische doelen; en de hypoglycemische makelaars.

Hoewel de informatie om optimale toedieningsbenaderingen te vinden beperkt is, is de algemene behoefte aan een extra ijverige methode om de behoeften van oudere mensen met diabetes te beoordelen om geïndividualiseerde zorgmethoden te vertellen en doelen te verhelpen die potentiële gevaren verminderen.